siTOOLs Biotech GmbH, Planegg (HRB 207818)

validated siRNA unwanted off-target effects target validation target identification target discovery sitoolsbiotech silencing gene expression siTOOLs Biotech siTOOLs siRNA technology siRNA screening siRNA protocol siRNA pool siRNA oligos siRNA off-target siRNA library siRNA dicer siRNA design tool siRNA design siRNA siPOOLs siPOOL shRNA ribozero ribosomal RNA depletion ribosomal RNA riboPOOL raPOOLs raPOOL rRNA removal rRNA depletion pulldown probes preclinical research phenotypic screening phenotypic comparison phenotypes pan-prokaryote on-target off-target siRNA off-target effects off-target microbe sequencing metagenomic sequencing lncRNA kinase library genetic tool gene-silencing gene validation gene silencing gene knock-down gene function gene expression gene deregulation functional genomic functional gene expression analysis drug discovery dicer designing siRNA biotinylated probes biotinylated oligo biotinylated DNA probe biotinylated DNA biotin probe bioinformatics RNAi transfection RNAi screening RNAi research RNAi pathway RNAi off-targets RNAi off-target effects RNAi mediated gene silencing RNAi mechanism RNAi knock-down RNAi dicer RNAi delivery RNAi company RNAi application RNAi RNA-Seq RNA pulldown RNA interference RNA binding protein library RNA affinity purification NGS ChIRP CRISPR